doc. Mgr. Kamil Paruch, Ph.D.

2018

• Inovativní inhibitor proteinu CHK1 indukuje apoptózu u buněk chronické lymfocytární leukémie s mutacemi v genu TP53

  BOUDNÝ Miroslav ZEMANOVÁ Jana KHIRSARIYA PrashantKumar BORSKÝ Marek VERNER Jan AMRUZ ČERNÁ Kateřina MRÁZ Marek OLTOVÁ Alexandra JAŠKOVÁ Zuzana ŠPUNAROVÁ Michaela ŠEDA Václav BRYCHTOVÁ Yvona MAYER Jiří PARUCH Kamil TRBUŠEK Martin

  Conference abstract

  Year: 2018, type: Conference abstract

• Preparation of 3,4-Substituted-5-Aminopyrazoles and 4 Substituted-2-Aminothiazoles

  HAVEL Štěpán KHIRSARIYA PrashantKumar AKAVARAM Naresh PARUCH Kamil CARBAIN Benoit Jean-Pierre

  Article in Periodical

  The Journal of Organic Chemistry, year: 2018, volume: roč. 83, edition: č. 24, DOI

• Preparation of nanostructured surfaces to influence hPSC behavior

  POSPÍŠIL Jakub BIDMANOVÁ Šárka HOVÁDKOVÁ Zuzana HRABOVSKÝ Miloš PARUCH Kamil DAMBORSKÝ Jiří HAMPL Aleš JAROŠ Josef

  Appeared in Conference without Proceedings

  Year: 2018, type: Appeared in Conference without Proceedings

• Pyrazolotriazines as inhibitors of nucleases

  DAMBORSKÝ Jiří NIKULENKOV Fedor SISÁKOVÁ Alexandra HAVEL Štěpán KREJČÍ Lumír CARBAIN Benoit, Jean-Pierre BREZOVSKÝ Jan DANIEL Lukáš PARUCH Kamil

  Patent

  Publisher: Japan Patent Office, state: Japan, patent's number: JP 6313906, year: 2018

• Pyrazolotriazines as inhibitors of nucleases

  DAMBORSKÝ Jiří NIKULENKOV Fedor SISÁKOVÁ Alexandra HAVEL Štěpán KREJČÍ Lumír CARBAIN Benoit Jean-Pierre BREZOVSKÝ Jan DANIEL Lukáš PARUCH Kamil

  Patent

  Publisher: USPTO, state: United States of America, patent's number: US 9969741 B2, year: 2018

• Selective CHK1 inhibitor MU380 exhibits single-agent activity against chronic lymphocytic leukemia cells with TP53 mutations

  BOUDNÝ Miroslav ZEMANOVÁ Jana KHIRSARIYA PrashantKumar BORSKÝ Marek VERNER Jan ČERNÁ Jana MRÁZ Marek OLTOVÁ Alexandra JAŠKOVÁ Zuzana ŠPUNAROVÁ Michaela ŠEDA Václav BRYCHTOVÁ Yvona MAYER Jiří PARUCH Kamil TRBUŠEK Martin

  Conference abstract

  Year: 2018, type: Conference abstract

2017

• A Concise Synthesis of Forskolin

  HYLSE Ondřej MAIER Lukáš KUČERA Roman PEREČKO Tomáš SVOBODOVÁ Aneta KUBALA Lukáš PARUCH Kamil ŠVENDA Jakub

  Article in Periodical

  Angewandte Chemie International Edition, year: 2017, volume: 2017, edition: 56, DOI

• ATR-Chk1 pathway as a therapeutic target for leukemia and lymphoma

  BOUDNÝ Miroslav OLTOVÁ Alexandra PARUCH Kamil TRBUŠEK Martin

  Conference abstract

  Year: 2017, type: Conference abstract

• BRCA1 or CDK12 loss sensitizes cells to CHK1 inhibitors

  PACULOVÁ Hana KRAMARA Juraj ŠIMEČKOVÁ Šárka FEDR Radek SOUČEK Karel HYLSE Ondřej PARUCH Kamil SVOBODA Marek MISTRÍK Martin KOHOUTEK Jiří

  Article in Periodical

  Tumor Biology, year: 2017, volume: 2017, edition: October, DOI

• Diastereoselective Flexible Synthesis of Carbocyclic C Nucleosides

  MAIER Lukáš KHIRSARIYA PrashantKumar HYLSE Ondřej ADLA Santosh Kumar ČERNOVÁ Lenka POLJAK Michal KRAJČOVIČOVÁ Soňa WEIS Erik DRÁPELA Stanislav SOUČEK Karel PARUCH Kamil

  Article in Periodical

  The Journal of Organic Chemistry, year: 2017, volume: 82, edition: 7, DOI