prof. RNDr. Jan Vondráček, Ph.D.

2019

• n-3 Polyunsaturated fatty acids alter benzo[a]pyrene metabolism and genotoxicity in human colon epithelial cell models

  TYLICHOVÁ Zuzana NECA Jiri TOPINKA Jan MILCOVA Alena HOFMANOVÁ Jiřina KOZUBÍK Alois MACHALA Miroslav VONDRÁČEK Jan

  Article in Periodical

  Food and Chemical Toxicology, year: 2019, volume: 124, edition: FEB 2019, DOI

2018

• Adaptive changes in global gene expression profile of lung carcinoma A549 cells acutely exposed to distinct types of AhR ligands

  PROCHÁZKOVÁ Jiřina STRAPÁČOVÁ Simona SVRŽKOVÁ Lucie ANDRYSÍK Zdeněk HYZDALOVA Martina HRUBÁ Eva PĚNČÍKOVÁ Kateřina LIBALOVA H TOPINKA J KLÉMA Jiří ESPINOSA JM VONDRÁČEK Jan MACHALA Miroslav

  Article in Periodical

  Toxicology Letters, year: 2018, volume: 292, DOI

• Aryl Hydrocarbon Receptor-Dependent Metabolism Plays a Significant Role in Estrogen-Like Effects of Polycyclic Aromatic Hydrocarbons on Cell Proliferation

  HYZDALOVA M. PIVNIČKA Jakub ZAPLETAL Ondřej VAZQUEZ-GOMEZ G. MATTHEWS J. NEČA Jiří PĚNČÍKOVÁ Kateřina MACHALA M. VONDRÁČEK Jan

  Article in Periodical

  Toxicological sciences, year: 2018, volume: 165, edition: 2, DOI

• Atropisomers of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) exhibit stereoselective effects on activation of nuclear receptors in vitro

  PĚNČÍKOVÁ Kateřina BRENEROVÁ Petra SVRŽKOVÁ Lucie HRUBÁ Eva PÁLKOVÁ Lenka VONDRÁČEK Jan HANS-JOACHIM Lehmler MACHALA Miroslav

  Article in Periodical

  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, year: 2018

• Butyrate and docosahexaenoic acid interact in alterations of specific lipid classes in differentiating colon cancer cells.

  TYLICHOVÁ Zuzana SLAVÍK Josef CIGANEK Miroslav OVESNÁ Petra KRČMÁŘ Pavel STRAKOVÁ Nicol MACHALA Miroslav KOZUBÍK Alois HOFMANOVÁ Jiřina VONDRÁČEK Jan

  Article in Periodical

  JOURNAL OF CELLULAR BIOCHEMISTRY, year: 2018, volume: 119, edition: 6, DOI

• In vitro profiling of toxic effects of prominent environmental lower-chlorinated PCB congeners linked with endocrine disruption and tumor promotion

  PĚNČÍKOVÁ Kateřina SVRŽKOVÁ Lucie STRAPÁČOVÁ Simona NEČA Jiří BARTOŇKOVÁ Iveta DVOŘÁK Zdeněk HÝŽĎALOVÁ Martina PIVNIČKA Jakub PÁLKOVÁ Lenka HANS-JOACHIM Lehmler LI Xueshu VONDRÁČEK Jan MACHALA Miroslav

  Article in Periodical

  ENVIRONMENTAL POLLUTION, year: 2018

• INHIBITION OF P300/CBP REDUCES CYP1A1 INDUCTION IN CANCER CELL MODELS DERIVED FROM THE LIVER OR COLON EPITHELIUM

  KRKOŠKA Martin SVOBODOVÁ Jana ZAPLETAL Ondřej KARASOVÁ Martina HYRŠLOVÁ VACULOVÁ Alena VONDRÁČEK Jan

  Conference abstract

  Year: 2018, type: Conference abstract

2017

• Activation of autophagy and PPAR gamma protect colon cancer cells against apoptosis induced by interactive effects of butyrate and DHA in a cell type-dependent manner: The role of cell differentiation

  TYLICHOVÁ Zuzana STRAKOVÁ Nicol VONDRÁČEK Jan VACULOVA A.H. KOZUBÍK Alois HOFMANOVÁ Jiřina

  Article in Periodical

  JOURNAL OF NUTRITIONAL BIOCHEMISTRY, year: 2017, volume: 39, edition: January, DOI

• Butyrate alters expression of cytochrome P450 1A1 and metabolism of benzo[a] pyrene via its histone deacetylase activity in colon epithelial cell models

  ZAPLETAL Ondřej TYLICHOVÁ Zuzana NEČA Jiří KOHOUTEK Jiří MACHALA Miroslav MILCOVA A. POKORNA Michaela TOPINKA Jan MOYER M.P. HOFMANOVÁ Jiřina KOZUBÍK Alois VONDRÁČEK Jan

  Article in Periodical

  ARCHIVES OF TOXICOLOGY, year: 2017, volume: 91, edition: 5, DOI

• Butyrate plays a supporting role in alterations of lipidome induced by DHA in colon cancer cells

  TYLICHOVÁ Zuzana SLAVÍK Josef CIGANEK Miroslav OVESNÁ Petra KRČMÁŘ Pavel STRAKOVÁ Nicol MACHALA Miroslav KOZUBÍK Alois VONDRÁČEK Jan HOFMANOVÁ Jiřina

  Conference abstract

  Year: 2017, type: Conference abstract