Mgr. Hana Kostrhunová, Ph.D.

2025

• A Novel Benzothiazole-1,2,3-Triazole-Based Arene Osmium(II) Complex as an Effective Rhabdomyosarcoma Cancer Stem Cell Agent

  SHARKAWY Sofia HERNÁNDEZ-GARCÍA Alba KOSTRHUNOVÁ Hana BAUTISTA Delia MARKOVÁ Lenka SANTANA María Dolores KAŠPÁRKOVÁ Jana BRABEC Viktor RUIZ José

  Article in Periodical

  Inorganic Chemistry Frontiers, year: 2025, volume: 12, DOI

2024

• Dicobalt(ii) helices kill colon cancer cells via enantiomer-specific mechanisms; DNA damage or microtubule disruption

  SONG Hualong KOSTRHUNOVÁ Hana ČERVINKA Jakub MACPHERSON Julie MALINA Jaroslav RAJAN Teena PHILLIPS Roger POSTINGS Miles SHEPHERD Samantha ZHANG Xuejian BRABEC Viktor ROGERS Nicola J SCOTT Peter

  Article in Periodical

  Chemical Science, year: 2024, volume: 15, edition: 28, DOI

• Effect of Osmium Complexes on Cancer Stem Cells in Rhabdomyosarcoma

  SHARKAWY Sofia KOSTRHUNOVÁ Hana

  Appeared in Conference without Proceedings

  Year: 2024, type: Appeared in Conference without Proceedings

• New cyclometalated Ru(ii) polypyridyl photosensitizers trigger oncosis in cancer cells by inducing damage to cellular membranes

  ČERVINKA Jakub HERNÁNDEZ-GARCÍA Alba BAUTISTA Delia MARKOVÁ Lenka KOSTRHUNOVÁ Hana MALINA Jaroslav KAŠPÁRKOVÁ Jana SANTANA M Dolores BRABEC Viktor RUIZ José

  Article in Periodical

  Inorganic Chemistry Frontiers, year: 2024, volume: 11, edition: 13, DOI

• Targeting CTG repeat expansions in DM1 cells using a supramolecular metal helicate

  ČERVINKA Jakub MALINA Jaroslav KOSTRHUNOVÁ Hana BRABEC Viktor

  Appeared in Conference without Proceedings

  Year: 2024, type: Appeared in Conference without Proceedings

2023

• N-Indolyl diiron vinyliminium complexes exhibit antiproliferative effects in cancer cells associated with disruption of mitochondrial homeostasis, ROS scavenging, and antioxidant activity

  BRESCIANI Giulio ČERVINKA Jakub KOSTRHUNOVÁ Hana BIANCALANA Lorenzo BORTOLUZZI Marco PAMPALONI Guido NOVOHRADSKÝ Vojtěch BRABEC Viktor MARCHETTI Fabio KAŠPÁRKOVÁ Jana

  Article in Periodical

  Chemico-Biological Interactions, year: 2023, volume: 385, edition: November, DOI

2012

• Cellular Response to Antitumor cis-Dichlorido Platinum(II) Complexes of CDK Inhibitor Bohemine and Its Analogues

  LISKOVA Barbora ZERZÁNKOVÁ Lenka NOVAKOVA Olga KOSTRHUNOVÁ Hana TRAVNICEK Zdenek BRABEC Viktor

  Article in Periodical

  CHEMICAL RESEARCH IN TOXICOLOGY, year: 2012, volume: 25, edition: 2, DOI

• Valuable Insight into the Anticancer Activity of the Platinum-Histone Deacetylase Inhibitor Conjugate, cis-[Pt(NH3)(2)malSAHA_(2H))]

  BRABEC Viktor GRIFFITH Darren M KISOVA Anna KOSTRHUNOVÁ Hana ZERZÁNKOVÁ Lenka MARMION Celine J KASPARKOVA Jana

  Article in Periodical

  MOLECULAR PHARMACEUTICS, year: 2012, volume: 9, edition: 7, DOI

2010

• Mechanistic insights into antitumor effects of new dinuclear cis Pt-II complexes containing aromatic linkers

  ZERZÁNKOVÁ Lenka KOSTRHUNOVÁ Hana VOJTISKOVA Marie NOVAKOVA Olga SUCHANKOVA Tereza LIN Miaoxin GUO Zijian KASPARKOVA Jana BRABEC Viktor

  Article in Periodical

  Biochemical Pharmacology, year: 2010, volume: 80, edition: 3, DOI