Project information
Czech National Infrastructure for Biological Data
(ELIXIR-CZ)
- Project Identification
- LM2015047
- Project Period
- 1/2016 - 12/2019
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- Large Infrastructures for Research, Development and Innovation
- MU Faculty or unit
-
Central European Institute of Technology
- prof. RNDr. Jaroslav Koča, DrSc.
- RNDr. Petr Kulhánek, Ph.D.
- Mgr. Martin Prokop, Ph.D.
- RNDr. Tomáš Raček, Ph.D.
- RNDr. David Sehnal, Ph.D.
- doc. RNDr. Radka Svobodová, Ph.D.
- prof. RNDr. Michaela Wimmerová, Ph.D.
- Other MU Faculty/Unit
-
Institute of Computer Science
- prof. RNDr. Luděk Matyska, CSc.
- Mgr. Ivana Křenková
- Mgr. Slávek Licehammer
- RNDr. Michal Procházka, Ph.D.
- Mgr. Zdeněk Salvet
- Project Website
- https://www.elixir-czech.cz/
- Cooperating Organization
-
Institute of Microbiology of the ASCR, v. v. i.
Institute of Molecular Genetics of the ASCR, v. v. i.
Institute of Organic Chemistry and Biochemistry of the ASCR, v. v. i.
- Responsible person RNDr. Jiří Vondrášek, CSc.
University of South Bohemia České Budějovice
Charles University
Palacký University, Olomouc
Prague Institute of Chemical Technology
St. Anne's University Hospital Brno
Biological Centre of the ASCR, v. v. i.
Institute of Biotechnology CAS
It is a current global trend that life science experiments generate an immense and steadily increasing volume of data. The Czech Republic feels this trend very strongly, because several new life science infrastructures were successfully established here, and they produce large amounts of data. It is necessary to store the data, safely manipulate with them, efficiently extract key information, etc. ELIXIR CZ is an infrastructure which is prepared to accept this challenge.
Thus, ELIXIR CZ aims to create a sustainable infrastructure for storing, processing and analysis of life science data in the Czech Republic. It will also provide tools and training that will facilitate performing these activities. Currently, ELIXIR CZ involves eleven institutions - nine life science research centres and two IT infrastructures. ELIXIR CZ also creates a communication platform for life science research institutes in the Czech Republic. ELIXIR CZ is a node of the European ESFRI project ELIXIR and is strongly involved in its activities. The ELIXIR project was approved by the Competitiveness Council from ESFRI as one of three prioritised Research Infrastructures.
Publications
Total number of publications: 68
2018
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Haloalkane Dehalogenases From Marine Organisms
MARINE ENZYMES AND SPECIALIZED METABOLISM, PT B, year: 2018, volume: 605, edition: 1, DOI
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HotSpot Wizard 3.0: web server for automated design of mutations and smart libraries based on sequence input information
Nucleic Acids Research, year: 2018, volume: 46, edition: W1, DOI
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ChannelsDB: database of biomacromolecular tunnels and pores
Nucleic Acids Research, year: 2018, volume: 46, edition: D1, DOI
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Impact of the access tunnel engineering on catalysis is strictly ligand-specific
the FEBS Journal, year: 2018, volume: 285/2018, edition: 8, DOI
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INTENSITYANALYSER: WEB TOOL FOR ASSESSMENT OF TELOMERE LENGTHS FROM TERMINAL RESTRICTION FRAGMENT ANALYSIS
15th International Interdisciplinary Meeting on Bioanalysis, year: 2018
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Molecular Gating of an Engineered Enzyme Captured in Real Time
Journal of the American Chemical Society, year: 2018, volume: 140, edition: 51, DOI
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MOLEonline: a web-based tool for analyzing channels, tunnels and pores (2018 update)
Nucleic Acids Research, year: 2018, volume: 46, edition: W1, DOI
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Validation of ligands in macromolecular structures determined by X-ray crystallography
Acta Crystallographica Section D, year: 2018, volume: 74, edition: 3, DOI
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Worldwide Protein Data Bank validation information: usage and trends
Acta Crystallographica Section D, year: 2018, volume: 74, edition: MAR, DOI
2017
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ALK5 kinase inhibitory activity and synthesis of 2,3,4-substituted 5,5-dimethyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazoles
European Journal of Medicinal Chemistry, year: 2017, volume: 2017, edition: 127, DOI